Biomolecular Free Radical Toxicity: Causes and Prevention

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Product Information:
ISBN-13: 9780471490760
ISBN-10: 0471490768
Publisher: Wiley
Format: Hardback, 256 pages
Pub Date: 12/2000
Edition Number: 1

Synopsis

Biomolecular Free Radical Toxicity: Causes and Prevention provides a comprehensive overview of biomolecular injury. By discussing recent research and providing interpretations of the available data, this unique and timely book explores the causes of biomolecular injury and the possible routes to its prevention. Split into three sections, the book covers:
* macromolecular mechanisms of injury and the role of anti oxidants;
* gene expression and cell mediated mechanisms of toxicity expression; and,
* human and environmental health effects.
Written by experts in the field, Biomolecular Free Radical Toxicity: Causes and Prevention will be invaluable to researchers specialising in food and nutrition-based toxicology, biomolecular sciences, biochemistry, genetics, environmental biomonitoring, drug metabolism and carcinogenesis.

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Additional Description

MACROMOLECULAR MECHANISMS OF INJURY AND THE ROLE OF ANTIOXIDANTS.

Membrane Lipid and Lipoprotein Injury: Prevention by Antioxidants (H. Wiseman &T. Ridgway).

DNA Injury: Prevention by Antioxidants (R. Hambly).

Protein Injury: Prevention by Antioxidants (B. Evans &J. Woodward).

GENE EXPRESSION AND CELL MEDIATED MECHANISMS OF TOXICITY EXPRESSION.

Xenobiotic Metabolism and Bioactivation by Cytochromes P-450 (C. Ioannides).

Apoptosis Triggered by Free Radicals: Role in Human Diseases (G. Kass, et al.).

HUMAN AND ENVIRONMENTAL HEALTH EFFECTS.

Dietary Phytoestrogens, Oestrogens and Tamoxifen: Mechanisms of Action in Modulation of Breast Cancer Risk and Prevention of Heart Disease (H. Wiseman).

Strategies for the Removal of Ecotoxicants: Environmental Oestrogens and Oestrogen-Mimics (T. Ridgway &H. Wiseman).

Index.