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Product Detail
Clinical Trials in Cardiovascular Disease: A Companion to Braunwald's Heart Disease
Charles H. Hennekens
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$131.00
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Product Information:
ISBN-13:
9780721668673
ISBN-10:
0721668674
Publisher:
SAUNDERS W B CO
Format:
Hardcover, 472 pages
Pub Date:
Edition Number:
1
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Synopsis
Here's a companion to the well-respected and popular HEART DISEASE 5th Edition by Braunwald. Expertly edited, this text offers an assessment of treatments for cardiovascular disease, and provides evidence for and against accepted therapies. Coverage includes an introduction to cardiovascular disease, methodology, treatment trials, prevention trials and much more! Features over 230 helpful illustrations.
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Additional Description
TABLE OF CONTENTS
SECTION I
METHODOLOGY 1
1 Contributions of Basic Research,
Observational Studies, and Randomized
Trials 3
Julie E. Buring
Charles H. Hennekens
2 Methodology of Randomized Trials 9
Laurence S. Freedman
3 Comparative Features of
Primordial, Primary, and Secondary
Prevention Trials 17
Lawrence M. Friedman
Denise G. Simons-Morton
Jeffrey A. Cutler
4 Large-Scale Randomized Trials 24
Colin Baigent
Rory Collins
Richard Peto
5 Principles of Data and Safety Monitoring
Boards in Randomized Trials 31
David L. DeMets
6 Meta-Analysis of
Randomized Trials 43
Graham A. Colditz
Catherine S. Berkey
Frederick Mosteller
SECTION II
TREATMENT TRIALS 53
PART I
Interventions for Acute Ischemia 55
7 Aspirin and Heparin 55
Colin Baigent
Rory Collins
8 Thrombolytic Therapy 65
Colin U. Baigent
Rory Collins
9 Beta Blockers 76
Claudia U. Chae
Charles H. Hennekens
10 Angiotensin-Converting Enzyme
Inhibitors 95
Marcus D. Flather
Marc A. Pfeffer
11 Calcium Channel Blockers 106
David Waters
12 Magnesium 119
Kent L. Woods
Hanne Berg Ravn
13 Nitrates 131
Ari D. Levinson
James L. Velianou
Salim Yusuf
14 Direct Thrombin Inhibitors 145
Elliott M. Antman
John A. Bittl
15 Platelet Glycoprotein IIb/IIIa Receptor
Inhibitors 166
Keaven M. Anderson
Harlan F. Weisman
Barry S. Coller
16 Primary Angioplasty, Rescue
Angioplasty, and New Devices 185
C. Michael Gibson
PART II
Interventions for Secondary Prevention 199
17 Lipid-Lowering Therapy 199
B. Greg Brown
Ex-Qiao Zhao
18 Antiarrhythmic Drug Therapy 217
William G. Stevenson
Peter L. Friedman
19 Antiarrhythmic Drug Therapy in
Supraventricular Tachycardia 231
Sharon C. Reimold
20 Antithrombotic and Anticoagulant
Therapy 245
David M. Kerins
Paul M. Ridker
21 Anticoagulant and Antiplatelet Drug
Therapy in Atrial Fibrillation 257
Daniel E. Singer
Elaine M. Hylek
22 Angioplasty and Bypass Surgery 267
Malcolm R. Bell
Bernard J. Gersh
23 Exercise 278
Barry A. Franklin
Peter A. McCullough
Gerald C. Timmis
24 Congestive Heart Failure 296
Norman Sharpe
25 Psychosocial Factors 315
Robert Allan
Stephen Scheidt
SECTION III
PREVENTION TRIALS 325
26 Cholesterol Reduction 327
J. Michael Gaziano
William P. Castelli
27 Blood Pressure Reduction 341
Paul K. Whelton
Jiang He
28 Smoking Cessation 361
Nancy A. Rigotti
Richard C. Pasternak
29 Exercise and Weight Loss 375
Marcia L. Stefanick
30 Aspirin 392
Julie E. Buring
Charles H. Hennekens
31 Postmenopausal Hormone Replacement
Therapy 399
Claudia U. Chae
JoAnn E. Manson
32 Antioxidant Vitamins 415
J. Michael Gaziano
JoAnn E. Manson
33 Dietary Factors 423
Frank M. Sacks
34 Multiple Risk Factor
Intervention Trials 432
Dean Ornish
Jacqueline A. Hart
35 Prevention Strategies: From the Office
to the Community 447
Ira S. Ockene
David Chiriboga
Index 461
END
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