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Contents
Preface vii
Contributors ix
1 Intracoronary brachytherapy: a new treatment for the
prevention of restenosis 1
Alexander J Wardeh, Ken Kozuma, Arie HM Knook,
Manel Sabate, 1 Patrick Kay, Patrick W Serruys
2 Therapeutic angiogenesis for coronary artery disease 21
Michael JB Kutryk, Saleem A Kassam,
Duncan J Stewart
3 Spot stenting 43
Antonio Colombo and Takahiro Nishida
4 Ostial and bifurcation disease 67
Alexander JR Black, Jean Fajadet, Jean Marco
5 Left main disease 83
Alexander JR Black, Jean Fajadet, Jean Marco
6 Small vessel stenting 95
Flavio Airoldi, Carlo DI Mario, Remo Albiero,
Antonio Colombo
7 Direct stenting 107
Sanjay Prasad, Ameet Bakhai, Ulrich Sigwart
8 Treatment of chronic total coronary occlusions 121
Christopher EH Buller, Jaap N Hamburger
9 In-stent restenosis 131
Raluca Arimie, David P Faxon
10 Restenosis, a pragmatic approach 141
David R Holmes
11 Percutaneous intervention in acute coronary syndromes
153
Michael J Curran, Cindy L Grines
12 Pediatric coronary artery abnormalities and interventions
185
Peter R Koenig, Ziyad M Hijazi
13 Post-angioplasty dissection 197
David Antoniucci
14 Alternative imaging 211
J Ligthart, Pim J de Feyter
15 Calcified and fibrotic lesions 237
Stefan Verheye, Glenn Van Langenhove,
Mahomed Y Salame
16 Ablative techniques 255
Glenn Van Langenhove, Stefan Verheye,
David P Foley
17 Direct myocardial revascularization: surgical and
catheter-based approaches 269
Shmuel Fuchs, Ran Kornowski,
Martin B Leon
18 Stent retrieval 283
Antonio Colombo, Goran Stankovic
19 Adjunctive therapies in percutaneous coronary
interventions 291
Thaddeus R Tolleson, Eric J Topol,
Robert A Harrington
20 Local drug delivery using drug-eluting stents 319
Yanming Huang, Eric Verbeken,
Etienne Schacht, Ivan De Scheerder
21 The significance of biochemical markers for myocardial
damage in interventional procedures 337
Nicholas M Robinson, Martin T Rothman
Index 359
Contributors
Flavio Airoldi, MD
Cardiac Catheterization Laboratory
EMO Centro Cuore Columbus
20145 Milan
Italy
Remo Albiero, MD
EMO Centro Cuore Columbus
20145 Milan
Italy
David Antoniucci, MD
Division of Cardiology
Ospedale di Careggi
85-50134 Florence
Italy
Raluca Arimie, MD
University of Southern California
Los Angeles CA
USA
Ameet Bakhai, MBBS, MRCP
Clinical Trials and Evaluations Unit
Imperial College School of Medicine
Royal Brompton Hospital
London SW3 6NP
UK
Alexander JR. Black, MD
Department of Cardiology
The Geelong Hospital
Geelong 3220
Australia
Christopher EH Buller, MD
Vancouver Hospital and Health Sciences Center
Department of Medicine
Vancouver BC V5Z 118
Canada
Antonio Colombo, MD
Director, Cardiac Catheterization Laboratory
EMO Centro Cuore Columbus
20145 Milan
Italy
Michael J Curran, MD, FACC
National Naval Medical Center
Bethesda MD 20889-5600
USA
Jean Fajadet, MD
Unite de Cardiologie Interventionelle
Clinique Pasteur
31076 Toulouse
France
David P Faxon, MD
Chief, Section of Cardiology
University of Chicago
Chicago IL 60637
USA
Pim J de Feyter, MD
University Hospital-Dijkzigt
Thoraxcenter
3000 CA Rotterdam
The Netherlands
David P Foley
University Hospital-Dijkzigt
Thoraxcenter
3000 CA Rotterdam
The Netherlands
Shmuel Fuchs, MD
Director, Interventional Myocardial
Angiogenesis
Cardiovascular Research Institute
Washington Hospital Center
Washington DC 20010
USA
Cindy L Grines, MD, FACC
Division of Cardiology
William Beaumont Hospital
Royal Oak MI 48073-6769
USA
Jaap N Hamburger, MD, PhD, FESC
Director of Research
Interventional Cardiology Program
St Paul's Hospital
Vancouver BC V6Z 1L7
Canada
Robert A Harrington, MD
Duke Clinical Research Institute
Durham NC 27707
USA
Ziyad Hijazi, MD
Chief, Section of Pediatric Cardiology
The University of Chicago Children's Hospital
Chicago IL 60637
USA
David R Holmes Jr, MD
Consultant in Cardiovascular Diseases and Internal
Medicine
Mayo Clinic Rochester MN 55905
USA
Yanming Huang, MD
Katholieke Universiteit Leuven
Campus Gasthuisberg
BE-3000 Leuven
Belgium
Saleem A Kassam, MD, MCE
Division of Cardiology
Terence Donnelly Heart Center
St Michael's Hospital
Toronto ON M5B 2W8
Canada
I Patrick Kay, MBChB
Department of Interventional Cardiology
Thoraxcenter
Academic Hospital Rotterdam-Dijkzigt
Rotterdam
The Netherlands
Arie HM Knook, MD
Department of Interventional Cardiology
Thoraxcenter
Academic Hospital Rotterdam-Dijkzigt
Rotterdam
The Netherlands
Peter R Koenig, MD
Assistant Professor of Clinical Pediatrics
University of Chicago Children's Hospital
Chicago IL 60637
USA
Ran Kornowski, MD, FACC
Director, Interventional Cardiology
Rabin Medical Center
Petach Tikva 49100
Israel
Ken Kozuma, MD
Department of Interventional Cardiology
Thoraxcenter
Academic Hospital Rotterdam-Dijkzigt
Rotterdam
The Netherlands
Michael JB Kutryk, MD, PhD
Division of Cardiology
Terence Donnelly Heart Center
St Michael's Hospital
Toronto ON M5B 2W8
Canada
Glenn van Langenhove, MD
Middelheim Hospital
2020 Antwerp
Belgium
Martin B Leon, MD
Director and CEO, Cardiovascular Research Foundation
Lenox Hill Heart and Vascular Institute
New York NY 10021
USA
J Ligthart
University Hospital-Dijkzigt
Thoraxcenter
3000 CA Rotterdam
The Netherlands
Jean Marco, MD
Unite de Cardiologie Interventionelle
Clinique Pasteur
31076 Toulouse
France
Carlo Di Mario, MD
Director of Research
EMO Centro Cuore Columbus
20145 Milan
Italy
Takahiro Nishida, MD
Research Fellow
EMO Centro Cuore Columbus
20145 Milan
Italy
Sanjay Prasad, BSc, MBChB, MRCP, MD
Royal Brompton Hospital
London SW3 6NP
UK
Nicholas M Robinson, MA, MD, MRCP
Consultant Cardiologist
London Chest Hospital
London E2 9JX
UK
Martin T Rothman, MB, ChB, FRCP, FACC, FESC
Consultant Cardiologist
London Chest Hospital
London E2 9JX
UK
Manel Sabate, MD
Department of Interventional Cardiology
Thoraxcenter
Academic Hospital RotterdamDijkzigt
Rotterdam
The Netherlands
Mahomed Y Salame, MRCP
Andreas Gruntzig Cardiovascular Center
Emory University Hospital
Atlanta GA 30322
USA
Etienne Schacht, PhD
Department of Organic Chemistry
University of Ghent
BE-9000 Ghent
Belgium
Ivan De Scheerder, MD, PhD
Professor, Invasive Cardiology
Katholieke Universiteit Leuven
Campus Gasthuisberg
BE3000 Leuven
Belgium
Patrick W Serruys, MD, PhD, FACC, FESC
Head, Interventional Cardiology
Catheterization Laboratory
Thoraxcenter
Academic Hospital Rotterdam-Dijkzigt
3015 GD Rotterdam
The Netherlands
Ulrich Sigwart, FRCP, FESC, FACC
Consultant Cardiologist
Royal Brompton National Heart & Lung Hospital
London SW3 6NP
UK
Goran Stankovic
Research Fellow
EMO Centro Cuore Columbus
20145 Milan
Italy
Duncan J Stewart, MD
Division of Cardiology
Terence Donnelly Heart Center
St Michael's Hospital
Toronto ON M5B 2W8
Canada
Thaddeus R Tolleson, MD
Division of Cardiology
Duke University Medical Center
Durham NC 27715
USA
Eric J Topol, MD
Department of Cardiology
The Cleveland Clinic Foundation
Cleveland OH 44195-0001
USA
Eric Verbeken, MD, PhD
Department of Histopathology
Katholieke Universiteit Leuven
Campus Gasthuisberg
BE-3000 Leuven
Belgium
Stefan Verheye, MD
Cardiovascular Translational Research
Institute, Middelheim, Antwerp, Belgium
and
Interventional Cardiology
Middelheim Hospital
2020 Antwerp
Belgium
Alexander J Wardeh, MD
Department of Interventional Cardiology
Thoraxcenter
Academic Hospital Rotterdam-Dijkzigt
Rotterdam
The Netherlands
