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Drug-Eluting Stents: Advanced Applications For The Management of Coronary Disease

Christopher White


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Drug-Eluting Stents: Advanced Applications For The Management of Coronary Disease Retail Price: $139.95
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Product Information:
ISBN-13: 9781842143032
ISBN-10: 1842143034
Publisher: CRC Press
Format: Hardcover, 168 pages
Pub Date: 07/2005
Edition Number: 1




Synopsis

Describes the pharmacologic basis of anti-proliferative stent coatings.

Contains balanced coverage of alternative therapeutic options such as bare-metal stents.

Provides comprehensive coverage of post-operative management.

This new text-atlas provides an update on the latest advances in the use of coated or drug-eluting stents in the management of coronary artery disease. The book begins with a review of the mechanisms of in-stent restenosis and the pharmacologic basis of anti-proliferative stent coatings, and the latest on materials used in the construction of the stents themselves. It presents updates on recent clinical trials of alternative therapies and clinical experience of drug-eluting stents. With a focus on patient selection and post-operative management including anti-platelet and anti-coagulation therapy, it concludes with the use of drug-eluting stents and the implications for healthcare policies.




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Additional Description

Contributors ix
Preface x
Acknowledgments xi
Part I Background 1 (30)
1 Introduction and overview
3 (4)
Christopher J White

2 Mechanisms of restenosis following percutaneous coronary interventions
7 (12)
Salman A Arain and John P Reilly

3 Drug-eluting stent platforms: antiproliferative drugs and polymer coatings
19 (12)
Albert W Chan

Part II Treatment of Restenosis 31 (36)
4 Trials of oral drug therapy to reduce restenosis
33 (8)
Jose A Silva

5 Non-stent devices to reduce restenosis
41 (16)
Srinivasa P Potluri and Jose A Silva

6 Clinical trials of bare metal stents to reduce restenosis
57 (10)
Jose A Silva

Part III Clinical Experience with Drug-Eluting Stents 67 (38)
7 Clinical trials: bare metal stents versus drug-eluting stents
69 (12)
Ali F Aboufares and Stephen R Ramee

8 Broader indications (off-label use) for coronary drug-eluting stents
81 (14)
Albert W Chan

9 Complications related to drug-eluting stents
95 (10)
Jose A Silva

Part IV Optimal Patient Management and Selection for Drug-Eluting Stents 105 (30)
10 Patient selection criteria for drug-eluting stents
107 (8)
Ali Morshedi-Meibodi and J Stephen Jenkins

11 Optimal antiplatelet and anticoagulation therapy for drug-eluting stents
115 (10)
Mahesh S Mulumudi and Tyrone J Collins

12 Optimal deployment strategies for drug-eluting stents
125 (10)
Georges A Feghali and Bahji N Khuri

Part V Cost-Benefit Analysis and Future Strategies for Drug-Eluting Stents 135 (14)
13 Cost analysis for coronary drug-eluting stents
137 (8)
John P Reilly

14 The future of drug-eluting stents
145 (4)
Christopher J White

Index 149