By Anthony C. Chang, MD, MBA, Director, Cardiac Intensive Care, Chief, Critical Care Cardiology, Texas Children's Hospital; Associate Professor of Pediatrics-Cardiology, Baylor College of Medicine, Houston, TX, USA; and Jeffrey Towbin, MD, Professor, Departments of Pediatrics and Molecular and Human Genetics, Co-Director Cardiovascular Genetics Clinic, Baylor College of Medicine, Houston TX