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Mechanical Circulatory Support: In Children / Towards / Myocardial / Recovery / Permanent

Edited by:M. Loebe; Edited by: E. Henning


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Mechanical Circulatory Support: In Children / Towards / Myocardial / Recovery / Permanent Retail Price: $69.95
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Product Information:
ISBN-13: 9783798510463
ISBN-10: 3798510466
Publisher: Steinkopff-Verlag Darmstadt
Format: Hardback
Pub Date: 04/1997
Edition Number: 1




Synopsis

After decades of laboratory investigations mechanical circulatory support for the failing heart has entered the clinical arena. Today, a growing number of patients with progressive myocardial failure awaiting cardiac transplantation is successfully bridged to transplantation with ventricular assist devices. The proceedings of the "Mechanical Circulatory Support"-meeting, held in Berlin, October 21-22, 1995, present new aspects of mechanical circulatory support, recent experience with MCS in newborns and children using specially developed small devices, and the results of long-term mechanical assistance. The ability of the myocardium to recover under pressure de-loading and reduced workload is discussed. All these topics open up new perspectives for the use of mechanical circulatory support, not only as a bridge to transplantation, but also as a definitive approach for treating patients with end-stage heart failure. Some of these concepts may even provide real alternatives to heart transplantation, these being sorely needed in light of the severe donor organ shortage. Regulatory as well as ethical aspects of the extended use of mechanical circulatory support systems and new technical developments in the field are discussed by internationally distinguished experts.



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TABLE OF CONTENTS
Introduction v
Welcome Address vii
Mechanical ventricular assist in children: Experience at the
Children's Hospital, Boston (1990-1995)
Nido, P.J. del., J.E. Mayer, R.A. Jonas 1
Mechanical circulatory support at the Royal Children's Hospital
Karl, Tom, R. 7
Individual center experiences in pediatric mechanical circulatory
support for bridge-to-transplant and myocardial recovery
Dabritz, S., B.J. Messmer 21
Extracorporeal circulatory support in pediatric cardiac
patients - The Berlin Experience
Alexi-Meskishvili, V.R. Hetzer, Y. Weng, K. Ishino,
E. Potapov, M. Loebe, E. Hennig, F. Uhlemann, P.E. Lange 33
Mechanical circulatory support in pediatric age: Experience
of Bergamo
Glauber, M., P. Ferrazzi 53
Discussion Session, October 21, 1995 61
What is dilated cardiomyopathy?
Kuhl, U., H.-P. Schultheiss 69
Agonistic anti-B1-adrenoceptor autoantibodies in the serum of
patients with dilated cardiomyopathy
Wallukat, G., A. Wollenberger 83
Weaning from mechanical support after complete recovery in
patients with idiopathic dilated cardiomyopathy
Mueller J., G. Wallukat, Yu-Guo Weng, M. Dandel,
S. Spiegelsberger, M. Loebe, R. Hetzer 93
Discussion Session, Morning of October 22, 1995 109
Introduction to Afternoon Session, October 22, 1995 118
Epidemiology of heart failure
Dietz, R. 119
On the way to permanent support: Battery-powered, vented
ventricular assist systems and other innovative new systems
Frazier, O.H. 125
The wearable Novacor LVAS at Henri Mondor Hospital
Loisance, D., D. Tixier, C. Baufreton, P. Le Besnerais 131
Long-term mechanical circulatory support
Korfer, R., A. El-Banayosy, O. Fey 137
Left ventricular assistance with Novacor device: the "Pavia
Experience"
Minzioni, G., M. Rinaldi, L., Martinelli, F. Pagani,
N. Pederzolli, M. Vigano 143
Long-term mechanical circulatory support: The Berlin Experience
Loebe, M., Y. Weng, E. Hennig, J. Muller, S. Spiegelsberger,
R. Hetzer 149
Mechanical circulatory support systems 1995 - New devices under
investigation
Hennig, E. 155
Prospects for permanent mechanical circulatory support
Watson, J.T. 185
Quality of life with ventricular assist devices
Albert, W., S. Kiekbusch, K. Koller, R. Hetzer 191
Lessons from the heart: Ethical reflections on the clinical
trials of the Jarvik-7
Fox, R.C. 207
Discussion Session, Afternoon of October 22, 1995 213
Closing remarks
Hetzer, R. 221
Author Index 223