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STRUCTURE, BIOCHEMISTRY, AND BIOPHYSICS
Structure of the Heart and Cardiac Muscle
Energetics and Energy Production
Energy Utilization (Work and Heat)
The Contractile Proteins
The Cytoskeleton
Active State, Length-Tension Relationship, and Cardiac Mechanics
Excitation-Contraction Coupling: Extracellular and Intracellular Calcium Cycles
SIGNAL TRANSDUCTION AND REGULATION
Signal Transduction: Functional Signaling
Signal Transduction: Proliferative Signaling
Regulation of Cardiac Muscle Performance: Functional and Proliferative Mechanisms
NORMAL PHYSIOLOGY
The Heart as a Muscular Pump
The Working Heart
Cardiac Ion Channels
The Cardiac Action Potential
CLINICAL PHYSIOLOGY
The Electrocardiogram
Arrhythmias
The Ischemic Heart
Heart Failure
