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TABLE OF CONTENTS
CHAPTER 1
AORTIC AND ARTERIAL ANEURYSMS
Mark A. Creager and Jonathan L. Halperin
The Normal Aorta 1.2
Classification of Aortic Aneurysms 1.3
Cystic Medial Necrosis and the Marfan Syndrome 1.4
Miscellaneous Causes of Aortic Aneurysmal Disease 1.6
Aortic Imaging Methods 1.7
Thoraco-abdominal Aortic Aneurysms 1.9
Abdominal Aortic Aneurysms 1.10
Peripheral Arterial Aneurysms 1.17
CHAPTER 2
AORTIC DISSECTION
Eric M. Isselbacher, Joaquin E. Cigarroa, and Kim A. Eagle
Pathogenesis 2.2
Classification 2.3
Clinical Manifestations 2.5
Diagnostic Techniques 2.7
Selecting an Imaging Modality 2.17
Early Medical and Operative Therapy 2.18
Survival and Late Follow-Up 2.20
CHAPTER 3
ARTERIAL OCCLUSIVE DISEASES OF THE EXTREMITIES
Alan T. Hirsch
Epidemiology of Peripheral Arterial Disease 3.2
Lower Extremity Arterial Anatomy, Limb Blood Flow,
and Symptoms 3.3
Natural History and Prognosis 3.4
Clinical Presentation 3.6
Diagnostic Evaluation 3.7
Arteriosclerosis Obliterans 3.10
Thromboangiitis Obliterans and Fibromuscular Dysplasia 3.21
Fibromuscular Dysplasia 3.23
Popliteal Entrapment Syndrome 3.24
Acute Arterial Occlusion 3.25
Atheroembolism 3.27
CHAPTER 4
RENAL VASCULAR DISEASE
Thomas G. Pickering
Overview 4.2
Animal Models of Renovascular Hypertension 4.2
Mechanisms of Human Renovascular Hypertension 4.5
History and Epidemiology 4.8
Diagnosis 4.10
CHAPTER 5
MESENTERIC VASCULAR DISEASE
Magruder C. Donaldson
Mesenteric Vascular Anatomy 5.2
Regulation of Mesenteric Blood Flow 5.4
Acute Mesenteric Ischemia 5.6
Chronic Mesenteric Ischemia 5.12
CHAPTER 6
CEREBROVASCULAR DISEASE
Frances E. Jensen and Mark A. Creager
Clinical Presentation 6.2
Diagnostic Tests 6.3
Treatment of Carotid Artery Disease 6.6
Vertebrobasilar Disease 6.12
Vasculitis 6.15
Cerebral Embolism 6.16
CHAPTER 7
EVALUATION AND MEDICAL MANAGEMENT OF THE VASCULAR SURGERY PARENT
Khether E. Raby
Cardiovascular Mortality in Patients with Vascular Disease 7.2
Risk Assessment Derived from Clinical Features 7.5
Exercise Testing 7.7
Dipyridamole-Thallium/Sestamibi Imaging 7.8
Echocardiography 7.12
Holter (Ambulatory) ECG Monitoring 7.14
Effect of Medical Management on Cardiac Risk 7.18
Effect of Coronary Artery Bypass Surgery on Cardiac Risk 7.20
Decision Analysis 7.21
CHAPTER 8
RAYNAUD'S PHENOMENON AND OTHER VASOSPASTIC DISORDERS
Marie Gerhard and Mark A. Creager
Raynaud's Phenomenon 8.2
Other Temperature-Related Disorders 8.12
CHAPTER 9
KAWASAKI DISEASE
Kathryn A. Taubert and Adnan S. Dajani
Epidemiology 9.2
Pathology 9.3
Diagnosis and Clinical Features 9.5
Laboratory Findings 9.12
Therapy and Long-Term Follow-Up 9.12
CHAPTER 10
LYMPHATIC DISEASE
John D. L. Bry and Thomas F. O'Donnell, Jr.
Anatomy and Physiology of the Lymphatic Circulation 10.2
Lymphedema Classification 10.4
Physical Findings and Diagnosis 10.5
Treatment of Lymphedema 10.9
CHAPTER 11
NEOPLASTIC AND NON-NEOPLASTIC VASCULAR TUMORS
Scott R. Granter and Janina A. Longtine
Benign Vascular Tumors 11.2
Vascular Tumors with Malignant Potential 11.9
CONTRIBUTORS
JOHN D. L. BRY, MD
Vascular Surgeon
Alta Bates Medical Center
Berkeley, California
JOAQUIN E. CIGARROA, MD
Fellow in Cardiology
Harvard Medical School
Massachusetts General Hospital
Boston, Massachusetts
MARK A. CREAGER, MD
Associate Professor
Harvard Medical School
Cardiovascular Division
Brigham and Women's Hospital
Boston, Massachusetts
ADNAN S. DAJANI, MD
Professor of Pediatrics
Wayne State University School of Medicine
Director, Division of Infectious Diseases
Children's Hospital of Michigan
Detroit, Michigan
MAGRUDER C. DONALDSON, MD
Associate Professor of Surged
Harvard Medical School
Division of Vascular Surgery
Brigham and Women's Hospital
Boston, Massachusetts
KIM A. EAGLE, MD
Associate Professor of Internal Medicine
University of Michigan Medical Center
Associate Chief, Division of Cardiology
Co-director, Heart Care Program
University of Michigan
MARIE GERHARD, MD
Instructor of Medicine
Harvard Medical School
Cardiovascular Division
Brigham and Women's Hospital
Boston, Massachusetts
SCOTT R. GRANTER, MD
Instructor in Pathology
Harvard Medical School
Associate Pathologist
Brigham and Women's Hospital
Boston, Massachusetts
JONATHAN L. HALPERIN, MD
Professor of Medicine
Mt. Sinai Hospital
Director, Cardiology Clinical Services
Cardiovascular Institute at Mt. Sinai Hospital
New York, New York
ALAN T. HIRSCH, MD
Assistant Professor of Medicine
Director, Vascular Medicine Program
University of Minnesota Medical School
University of Minnesota Hospital and Clinic
Minneapolis, Minnesota
ERIC M. ISSELBACHER, MD
Graduate Assistant in Medicine
Harvard Medical School
Massachusetts General Hospital
Boston, Massachusetts
FRANCES E. JENSEN, MD
Assistant Professor of Neurology
Harvard Medical School
Children's Hospital Medical Center
Brigham and Women's Hospital
Boston, Massachusetts
JANINA A. LONGTINE, MD
Assistant Professor of Pathology
Harvard Medical School
Pathologist
Brigham and Women's Hospital
Boston, Massachusetts
THOMAS F. O'DONNELL, JR., MD
Professor of Surgery
Tufts University
Professor and Chairman
Department of Surgery
Chief, Vascular Surgery
New England Medical Center
Boston, Massachusetts
THOMAS G. PICKERING, MD, DPhil, FRCP
Professor of Medicine
Attending Physician
New York Hospital-Cornell Medical Center
New York, New York
KHETHER E. RABY, MD
Assistant Professor of Medicine
Harvard Medical School
Associate Physician
Brigham and Women's Hospital
Boston, Massachusetts
KATHRYN A. TAUBERT, PhD
Adjunct Associate Professor
The University of Texas Southwestern Medical School
Senior Science Consultant
American Heart Association
Dallas, Texas
